Sanofi, one of Massachusetts’ largest pharmaceutical employers, will lay off 229 workers, according to records the company filed with the state.

The workers losing their jobs have been employed with Blueprint Medicines, a Cambridge-based biotech that Sanofi acquired in a $9.1 billion deal in July 2025.

The workers’ positions will be cut between Oct. 9 and late June 2027, according to the filing with the state’s Executive Office of Labor and Workforce Development.